Professor of Bioengineering
- Bourns College of Engineering
General Overview: Dr. Anvari’s research is directed towards development and application of photonics-based instrumentation to obtain quantitative information that will provide insight into the fundamental mechanisms underlying a biological phenomenon, and to achieve effective optical modalities for diagnosis and therapy of specific tissue malformations. Specific Areas: Current research in Dr. Anvari’s laboratory is focused on: (1) investigating the nanoelectromechanical characteristics of cell membranes, particularly as they relate to the electromechanics of the outer hair cells within the cochlea; and (2) use of exogenous chromophores to enhance optical diagnosis and therapy of tissue malformations.
- B.A. Biophysics 1985
- University of California, Berkeley
- M.S. Biomedical Engineering 1988
- California State University, Sacramento
- Ph.D. Bioengineering 1993
- Texas A&M University
2011 American Association for the Advancement of Science (AAAS) Fellow
2008 Fellow, American Institute for Medical and Biological Engineering (AIMBE)
2006 NIH/NIDCD R01 Grant
2005 Biophotonics Partnership Initiative Program, National Science Foundation
2002 Texas Higher Education Coordinating Board Technology Development and Transfer grant
2001 NIH/NIDCD R01 Grant
2001 NIH/NIAMSD R01 Grant
1996 Whitaker Foundation Biomedical Engineering Research Grant
1996 National Science Foundation Bioengineering Research Grant
1996 NIH/NIHLB R15 Grant
Electromechanics of outer hair cells and biomembranes; Use of exogenous chromophores for optical imaging and therapy
K. R. Schumacher, A. S. Popel, B. Anvari, W. E. Brownell, and A. A. Spector, “Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane,” Journal of Biomechanical Engineering, 130 (3):031007, 2008.
M. A. Yasseen, J. Yu, M. S. Wong, and B. Anvari, “Laser-induced heating of dextran-coated mesocapsules containing indocyanine green,” Biotechnology Progress, 23: 1431-1440, 2007.
M. A. Yasseen, J. Yu, M. S. Wong, and B. Anvari, “Stability assessment of indocyanine green within dextran-coated mesocapsules by absorption spectroscopy,” Journal of Biomedical Optics, 12(6):064031, 2007.
R. Zhang, F. Qian, L. Rajagoplan, F. A. Pereira, W. E. Brownell, and B. Anvari, “Prestin modulates mechanics and electromechanical force of the plasma membrane,” Biophysical Journal, 10.1529/biophysj.107.107573, 2007..
G. I. Wenzel, B. Anvari, A. Mazhar, B. Pikkula, and J. S. Oghalai, “Laser-induced collagen remodeling and deposition within the basilar membrane of the mouse cochlea” Journal of Biomedical Optics, 12: 021007, 2007.
J. Yu, M. A. Yaseen, B. Anvari, and M. S. Wong, “Synthesis of Near-Infrared-Absorbing Nanoparticle-Assembled Capsules,” Chemistry of Materials, 19: 1277-1284, 2007.
O. Gliko, G. D. Reddy, B. Anvari, W. E. Brownell, and P. Saggau, “Standing wave total internal reflection fluorescence microscopy to measure the size of nanostructures in living cells,” Journal of Biomedical Optics, 6:064013, 2006.
S. Ermilov, D. R. Murdock, F. Qian, W. E. Brownell, and B. Anvari, “Studies of plasma membrane mechanics and plasma membrane-cytoskeleton interactions using optical tweezers and fluorescence imaging,” Journal of Biomechanics, doi:10.1016/j.biomech.2005.12.006, 2006.
D. R. Murdock, S. Ermilov, A. A. Spector, A. S. Popel, W. E. Brownell, and B. Anvari, “Effects of chlorpromazine on mechanical properties of outer hair cell plasma membrane,” Biophysical Journal, 89: 4090-4095, 2005.
M. Arya, G. M. Romo, M. A. Cruz, Jose A. Lopez, and B. Anvari, “Dynamic force spectroscopy glycoprotein Ib-IX and von Willebrand factor,” Biophysical Journal, 88: 4391-4401, 2005.
S. Ermilov, D. R. Murdock, D. El-Daye, W. E. Brownell, and B. Anvari, “Effects of salicylate on plasma membrane mechanics,” Journal of Neurophysiology, 94: 2105-2110, 2005.
B. Anvari, J. H. Torres, and B. W. McIntyre, “Regulation of pseudopodia localization in lymphocytes through application of mechanical forces by optical tweezers,” Journal of Biomedical Optics, 9: 865-872, 2004.
K. H. Simpson, G. Bowden, M. Arya, M. Höök, and B. Anvari, “Adherence of Staphylococcus aureus fibronectin binding protein A mutants: an investigation using optical tweezers,” Biomolecular Engineering, 21: 105-111, 2004.
S. Ermilov, and B. Anvari, “Dynamic measurements of transverse optical trapping force in biological applications,” Annals of Biomedical Engineering, 32: 1016-1026, 2004.
F. Qian, S. Ermilov, D. Murdock, W. E. Brownell, and B. Anvari; “Combining optical tweezers and patch clamp techniques for studies of cell membrane electromechanics,” Review of Scientific Instruments, 75: 2937-2942, 2004.
G. I. Wenzel, B. Pikkula, C. H. Choi, B. Anvari, and J. Oghalai, “Laser irradiation of the guinea pig cochlea basilar membrane,” Lasers in Surgery and Medicine, 35: 174-180, 2004.